Relating Histopathology and Mechanical Strain in Experimental Contusion Spinal Cord Injury in a Rat Model
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چکیده
منابع مشابه
Relating Histopathology and Mechanical Strain in Experimental Contusion Spinal Cord Injury in a Rat Model
During traumatic spinal cord injury (SCI), the spinal cord is subject to external displacements that result in damage of neural tissues. These displacements produce complex internal deformations, or strains, of the spinal cord parenchyma. The aim of this study is to determine a relationship between these internal strains during SCI and primary damage to spinal cord gray matter (GM) in an in viv...
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Objective- The current study was conducted to evaluate changes in the urinary bladder structure and leukocyte profile as an important index of the systemic inflammation response for two different types of spinal cord injury (SCI) in a rat model. Design- Experimental Study.Animals- Forty adult healthy female Sprague-Dawley rats.<br /...
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The translational potential of novel treatments should be investigated in severe spinal cord injury (SCI) contusion models. A detailed methodology is described to obtain a consistent model of severe SCI. Use of a stereotactic frame and computer controlled impactor allows for creation of reproducible injury. Hypothermia and urinary tract infection pose significant challenges in the post-operativ...
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ژورنال
عنوان ژورنال: Journal of Neurotrauma
سال: 2016
ISSN: 0897-7151,1557-9042
DOI: 10.1089/neu.2015.4200